• Product NameRTN4IP1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total RTN4IP1 protein.
• Immunogen Typepeptide
• Immunogen DescriptionSynthetic peptide corresponding to internal residues of human RTN4IP1
• Target NameRTN4IP1
• Alternative Names    NIMP; OPA10
• Accession No. Swiss-Prot:Q8WWV3
  NCBI Gene ID:84816
  NCBI Protein:NP_116119
• UniprotQ8WWV3
• Gene ID84816;
• Concentration 1.9mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1: 40-200

This gene encodes a mitochondrial protein that interacts with reticulon 4, which is a potent inhibitor of regeneration following spinal cord injury. This interaction may be important for reticulon-induced inhibition of neurite growth. Mutations in this gene can cause optic atrophy 10, with or without ataxia, mental retardation, and seizures. There is a pseudogene for this gene on chromosome 12. Alternative splicing results in multiple transcript variants.

• The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 46663(RTN4IP1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200)
• The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 46663(RTN4IP1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting