• Product NameZPR1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification
• ApplicationsWB IHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total ZPR1 protein.
• Immunogen Typepeptide
• Immunogen DescriptionSynthetic protein corresponding to residues near the C terminal of human ZPR1
• Target NameZPR1
• Alternative Names    ZNF259
• Accession No. Swiss-Prot:O75312
  NCBI Gene ID:8882
  NCBI Protein:BC004256
• UniprotO75312
• Gene ID8882;
• Calculated MW 51 kDa
• Concentration 0.9mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500-1:2000
  Immunohistochemistry: 1: 30-150

The protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells. The encoded protein interacts with survival motor neuron protein (SMN1) to enhance pre-mRNA splicing and to induce neuronal differentiation and axonal growth. Defects in this gene or the SMN1 gene can cause spinal muscular atrophy. Two transcript variants encoding different isoforms have been found for this gene.

• Gel: 8%SDS-PAGE
  lysate: 40 ¦Ìg, Lane 1-5: Hela£¬HEPG2£¬231£¬A431 and Jurkat cell lysates,
  Primary antibody: 46722£¨ZPR1 Antibody) at dilution 1/400 dilution,
  Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,
  Exposure time: 20 seconds
• The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 46722(ZPR1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200)
• The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 46722(ZPR1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting