• Product NameTLR2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationTLR2 Antibody is affinity chromatography purified via peptide column.
• ApplicationsELISA WB IHC
• Species ReactivityHu Ms
• Immunogen TypePeptide
• Immunogen DescriptionRaised against a peptide corresponding to 14 amino acids near the amino terminus of human TLR2.
• Target NameTLR2
• Alternative Names    TIRAP, MAL, TIR domain containing adaptor protein
• Accession No. O60603
• UniprotO60603
• Gene ID7097;
• Concentration 1mg/ml
• Formulation Supplied in PBS containing 0.02% sodium azide.
• Storage Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-κB. TLR2 can form heterodimers with either TLR1 or TLR6, and as a heterodimer can recognize a variety of bacterial and mycoplasma lipoproteins respectively.

• Western blot analysis of TLR2 in A20 cell lysates with TLR2 antibody at 1 ug/mL in the presence (A) and absence (B) of its blocking peptide.
• Immunohistochemical staining of human spleen cells using TLR2 antibody at 2 ug/mL.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting