• Product NameSFRP1 Rabbit Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB,IHC
• Species ReactivityHuman,Mouse
• Immunogen DescriptionRecombinant fusion protein of human SFRP1 (NP_003003.3).
• Alternative Names    SFRP1;FRP;FRP-1;FRP1;FrzA;SARP2
• Accession No. Swiss Prot:Q8N474
  GeneID:6422
• UniprotQ8N474
• Calculated MW 35kDa
• SDS-PAGE MW 35kDa
• Formulation Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Storage Store at -20˚C. Avoid freeze / thaw cycles.

• WB 1:100 - 1:500
  IHC 1:50 - 1:100

This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.

• Western blot analysis of extracts of various cell lines, using SFRP1 at 1:1000 dilution.
• Immunohistochemistry of paraffin-embedded human stomach using SFRP1 at dilution of 1:50 (20x lens).

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting