• Product NameGALC Rabbit Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB,IHC
• Species ReactivityHuman,Mouse,Rat
• Immunogen DescriptionRecombinant fusion protein of human GALC (NP_000144.2).
• Alternative Names    GALC
• Accession No. Swiss Prot:P54803
  GeneID:2581
• UniprotP54803
• Calculated MW 67kDa/74kDa/77kDa
• SDS-PAGE MW 77kDa
• Formulation Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Storage Store at -20˚C. Avoid freeze / thaw cycles.

• WB 1:500 - 1:2000
  IHC 1:50 - 1:100

This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

• Western blot analysis of extracts of various cell lines, using GALC at 1:1000 dilution.
• Immunohistochemistry of paraffin-embedded human liver cancer using GALC at dilution of 1:100 (40x lens).
• Immunohistochemistry of paraffin-embedded mouse testis using GALC at dilution of 1:100 (40x lens).
• Immunohistochemistry of paraffin-embedded mouse kidney using GALC at dilution of 1:100 (40x lens).

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting