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EGFR(Phospho-Tyr1172) Antibody #11220

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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
Availability:Yes
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Description
  • Product NameEGFR(Phospho-Tyr1172) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB IHC
  • Species ReactivityHu Ms Rt
  • SpecificityThe antibody detects endogenous level EGFR only when phosphorylated at tyrosine 1172.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around phosphorylation site of tyrosine 1172 (P-D-Y(p)-Q-Q) derived from Human EGFR.
  • Target NameEGFR
  • ModificationPhospho
  • Alternative Names    ERBB1; Receptor protein-tyrosine kinase ErbB-1; kinase EGFR
  • Accession No. Swiss-Prot: P00533
    NCBI Protein: NP_005219.2
  • UniprotP00533
  • Gene ID1956;
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

Tumor-penetrating Peptide Fused EGFR Single-Domain Antibody Enhances Cancer Drug Penetration Into 3D Multicellular Spheroids and Facilitates Effective Gastric Cancer Therapy .In J Control Release on 2015 Feb 28 by Huizi Sha , Zhengyun Zou et al..PMID: 25553823, , (2015),
PMID: 25553823
EGFR phosphorylation of DCBLD2 recruits TRAF6 and stimulates AKT-promoted tumorigenesis. In J Clin Invest on 2014 Sep by An-Jey A Su, Philip E Auron, et al..PMID:25061874 , , (2014),
PMID: 25061874
Epidermal Growth Factor (EGF)-enhanced Vascular Cell Adhesion molecule-1 (VCAM-1) Expression Promotes Macrophage and Glioblastoma Cell Interaction and Tumor Cell Invasion.In J Biol Chem on 2013 Nov 1 by Yanhua Zheng, Weiwei Yang,et al..PMID:24045955, , (2013),
PMID: 24045955
Epidermal Growth Factor (EGF)-enhanced Vascular Cell Adhesion molecule-1 (VCAM-1) Expression Promotes Macrophage and Glioblastoma Cell Interaction and Tumor Cell Invasion.In J Biol Chem on 2013 Nov 1 by Yanhua Zheng, Weiwei Yang,et al..PMID:24045955, , (2013),
PMID: 24045955
View All Published Papers Epidermal Growth Factor (EGF)-enhanced Vascular Cell Adhesion molecule-1 (VCAM-1) Expression Promotes Macrophage and Glioblastoma Cell Interaction and Tumor Cell Invasion.In J Biol Chem on 2013 Nov 1 by Yanhua Zheng, Weiwei Yang,et al..PMID:24045955, , (2013),
PMID: 24045955
ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect.In Nat Cell Biol on 2012 Dec by Weiwei Yang, Yanhua Zheng,et al..PMID:23178880, , (2012),
PMID: 23178880
EGFR-induced and PKCε monoubiquitylation-dependent NF-kB activation upregulates PKM2 expression and promotes tumorigenesis. In Mol Cell on 2012 Dec 14 by Weiwei Yang, Yan Xia, et al..PMID: 23123196, , (2012),
PMID: 23123196
PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis. In Cell on 2012 Aug 17 by Weiwei Yang, Yan Xia, et al..PMID: 22901803, , (2012),
PMID: 22901803
Please let us know if you have published research using #11220 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep