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IRS-1(Phospho-Ser636) Antibody #11230

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Catalog No. Package Size Price Quantity
50ul $189.00
100ul $279.00
Availability:Yes
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Description
  • Product NameIRS-1(Phospho-Ser636) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB IHC
  • Species ReactivityHu Ms Rt
  • SpecificityThe antibody detects endogenous level of total IRS-1 protein.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around phosphorylation site of serine 636 (P-M-S(p)-P-K) derived from Human IRS-1.
  • Target NameIRS-1
  • ModificationPhospho
  • Alternative Names    IRS-1; IRS1;
  • Accession No. Swiss-Prot: P35568
    NCBI Protein: NP_005535.1
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

Gema Marín-Royo,Cristina Rodríguez,Aliaume Le Pape,Raquel Jurado-López,María Luaces,Alfonso Antequera,José Martínez-González,Francisco V Souza-Neto,María Luisa Nieto,Ernesto Martínez-Martínez#,Victoria Cachofeiro# The Role of Mitochondrial Oxidative Stress in the Metabolic Alterations in Diet-Induced Obesity in Rats, FASEB J, 2019 Nov;33(11):12060-12072. (2019),
PMID: 31370681
Ling Wang,Ying-Qi Zhai,Li-Li Xu,Chen Qiao,Xiu-Lan Sun,Jian-Hua Ding,Ming Lu,Gang Hu Metabolic Inflammation Exacerbates Dopaminergic Neuronal Degeneration in Response to Acute MPTP Challenge in Type 2 Diabetes Mice, Exp Neurol, 2014 Jan;251:22-9. (2014),
PMID: 24220636
Please let us know if you have published research using #11230 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep