• Product NameTRPC3 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAffinity chromatography purified via peptide column
• ApplicationsELISA WB IHC
• Species ReactivityHu Ms
• Immunogen TypePeptide
• Immunogen DescriptionRaised against a 14 amino acid peptide from near the amino terminus of human TRPC3.
• Target NameTRPC3
• Alternative Names    Short transient receptor potential channel 3, Trpc3, Htrp3
• Accession No. Swiss-Prot:Q13507
  Gene ID:7222
• UniprotQ13507
• Gene ID7222;
• Concentration 1mg/ml
• Formulation Supplied in PBS containing 0.02% sodium azide.
• Storage Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

The mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the "canonical TRP"(TRPC) family. The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types. Furthermore, the members of the TRPC3/6/7 subfamily can be activated by diacylglycerol analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors. TRPC3 encodes a Ca2+-permeant channel that is agonist-activated but not store-operated or directly receptor-activated. TRPC3 physically interacts with TRPC6 and TRPC7 and forms functional tetrameric channels.

• Western blot analysis of TRPC3 in mouse heart tissue lysate with TRPC3 antibody at (A) 1 and (B) 2 ug/mL.
• Immunohistochemistry of TRPC3 in mouse heart tissue with TRPC3 antibody at 10 ug/mL.
• Western blot analysis of TRPC3 in human heart tissue lysate with TRPC3 antibody at (A) 1 and (B) 2 μg/mL.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting