• Product NameUnc93a Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAffinity chromatography purified via peptide column
• ApplicationsELISA WB
• Species ReactivityHu
• SpecificityTwo isoforms of Unc93a are known to exist. This antibody will not cross-react with Unc93b.
• Immunogen TypePeptide
• Immunogen DescriptionRaised against a 18 amino acid peptide from near the carboxy terminus of human Unc93a.
• Target NameUnc93a
• Alternative Names    Unc93a, homolog of C. elegans Unc93
• Accession No. Swiss-Prot:Q86WB7
  Gene ID:54346
• UniprotQ86WB7
• Gene ID54346;
• Concentration 1mg/ml
• Formulation Supplied in PBS containing 0.02% sodium azide.
• Storage Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Unc93a, a human homolog of the C. elegans Unc93 gene, was initially identified by the sequencing of chromosome 6q27 at D6S193 as loss at this region correlated with sporadic ovarian cancer. Further analysis however, showed no tumor suppressor role for Unc93a. Unlike Unc93b, another homolog of the C. elegans Unc93 gene that is crucial for Toll-like receptor (TLR) signaling, the function of Unc93a is unknown. It is expressed in testis, small intestine, spleen, prostate and ovary.

• Western blot analysis of Unc93a in HeLa cell lysate with Unc93a antibody at (A) 0.5 and (B) 1 ug/mL.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting