• Product NameMettL7B Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAffinity chromatography purified via peptide column
• ApplicationsELISA WB IHC
• Species ReactivityHu Ms
• SpecificityThis MettL7B antibody is predicted to not cross-react with MettL7A.
• Immunogen TypePeptide
• Immunogen DescriptionRaised against a 13 amino acid peptide near the amino terminus of human MettL7B.
• Target NameMettL7B
• Alternative Names    Methyltransferase-like protein 7B
• Accession No. Swiss-Prot:Q6UX53
  Gene ID:196410
• UniprotQ6UX53
• Gene ID196410;
• Concentration 1mg/ml
• Formulation Supplied in PBS containing 0.02% sodium azide.
• Storage Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

MettL7B belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.

• Western blot analysis of MettL7B in Jurkat lysate with MettL7B antibody at (A) 2 and (B) 4 ug/mL.
• Immunohistochemistry of MettL7B in human spleen tissue with MettL7B antibody at 2.5 ug/mL.
• Western blot analysis of MettL7B in human colon tissue lysate with MettL7B antibody at (A) 1 and (B) 2 μg/mL.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting