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AGTR1 Antibody

24966
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  Catalog No. Package Size Price
24966 100ul $469.00

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Description
  • Product Name AGTR1 Antibody
  • Host Species Rabbit
  • Clonality Polyclonal
  • Purification Affinity chromatography purified via peptide column
  • Applications ELISA WB IHC
  • Species Reactivity Hu Ms Rt
  • Immunogen Type Peptide
  • Immunogen Description Raised against a 16 amino acid peptide from near the center of human AGTR1.
  • Target Name AGTR1
  • Alternative Names Angiotensin II receptor type 1, Ang II, AT1, AT1R
  • Accession No. Swiss-Prot:P30556
    Gene ID:185
  • Concentration 1mg/ml
  • Formulation Supplied in PBS containing 0.02% sodium azide.
  • Storage Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Images
  • AGTR1 Antibody - SAB | Signalway Antibody

    Western blot analysis of AGTR1 in mouse kidney tissue lysate with AGTR1 antibody at (A) 1 and (B) 2 ug/mL.

  • AGTR1 Antibody - SAB | Signalway Antibody

    Immunohistochemistry of AGTR1 in mouse kidney tissue with AGTR1 antibody at 2.5 ug/mL.

Background
Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. AGTR1, the type 1 receptor, is thought to mediate the major cardiovascular effects of angiotensin II and may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. AGTR1 has recently been found to regulate the differentiation of bone marrow-derived monocyte lineage progenitors from hematopoietic stem cells, indicating the diversity of the roles of AGTR1.
    Please let us know if you have published research using #24966 so that we can cite your reference.
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    Protocol
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    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  
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