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Smad2(Phospho-Ser467) Antibody #11322

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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
Availability:Yes
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Description
  • Product NameSmad2(Phospho-Ser467) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB IHC
  • Species ReactivityHu Ms Rt
  • SpecificityThe antibody detects endogenous level of Smad2 only when phosphorylated at serine 467.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around phosphorylation site of serine 467 (C-S-S-M-S(p)) derived from Human Smad2.
  • Target NameSmad2
  • ModificationPhospho
  • Alternative Names    JV18-1; MADH2; MADR2; Mad-related protein 2; Mothers against DPP homolog 2
  • Uniprot Q15796
  • Gene ID 4087;
  • Accession No. Swiss-Prot: Q15796
    NCBI Protein: NP _001003652.1
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

TGFβ1 promotes gemcitabine resistance through regulating the LncRNA-LET/NF90/miR-145 signaling axis in bladder cancer.In Theranostics on 2017 Jul 22 by Junlong Zhuang, Lan Shen,et al..PMID: 28839463, , (2017),
PMID: 28839463
Inhibition of TGFβ signaling decreases osteogenic differentiation of fibrodysplasia ossificans progressiva fibroblasts in a novel in vitro model of the disease.In Bone.On 2016 Mar by Micha D, Voermans E et al..PMID:26769004, , (2016),
PMID: 26769004
Methotrexate-induced epithelial�Cmesenchymal transition in the alveolar epithelial cell line A549.In Lung on 2016 Dec by Masashi Kawami, Rika Harabayashi et al..PMID: 27604426 , , (2016),
PMID: 27604426
TGFβ1 secreted by cancer-associated fibroblasts induces epithelial-mesenchymal transition of bladder cancer cells through lncRNA-ZEB2NAT.In Sci Rep on 2015 Jul 8 by Junlong Zhuang , Qun Lu et al..PMID:26152796, , (2015),
PMID: 26152796
View All Published Papers SMAD2 Mutations Are Associated with Arterial Aneurysms and Dissections. In Hum Mutat on 2015 Dec by Dimitra Micha, Dong-Chuan Guo,et al..PMID:26247899, , (2015),
PMID: 26247899
High glucose increases Cdk5 activity in podocytes via transforming growth factor-β1 signaling pathway.In Exp Cell Res on 2014 Aug 15 by Yue Zhang, Hongbo Li et al..PMID: 24768698 , , (2014),
PMID: 24768698
The role of SIRT6 in the differentiation of vascular smooth muscle cells in response to cyclic strain.In Int J Biochem Cell Biol on 2014 Apr by Qing-Ping Yao, Ping Zhang et al..PMID: 24495875, , (2014),
PMID: 24495875
Induction of thoracic aortic remodeling by endothelial-specific deletion of microRNA-21 in mice. In PLoS One on 2013 by Xing-Yi Zhang, Bao-Rong Shen, et al..PMID: 23527070, , (2013),
PMID: 23527070
Induction of thoracic aortic remodeling by endothelial-specific deletion of microRNA-21 in mice. In PLoS One on 2013 by Xing-Yi Zhang, Bao-Rong Shen, et al..PMID: 23527070, , (2013),
PMID: 23527070
Please let us know if you have published research using #11322 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep