• Product NameFAM59B Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAffinity chromatography purified via peptide column
• ApplicationsELISA WB IHC
• Species ReactivityHu Ms Rt
• Immunogen TypePeptide
• Immunogen DescriptionRaised against a 19 amino acid peptide from near the carboxy terminus of human FAM59B.
• Target NameFAM59B
• Alternative Names    FLJ00375, KIAA2038
• Accession No. Q75VX8
• UniprotQ75VX8
• Gene ID150946;
• Concentration 1mg/ml
• Formulation Supplied in PBS containing 0.02% sodium azide.
• Storage Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

FAM59B is related to the FAM59A protein (also known as GAREM). While little is known of the role of the FAM59B protein, FAM59A is a downstream molecule in the EGF signaling pathway and binds Grb2, an adaptor protein crucial to the transduction of growth signals from the plasma membrane to the nucleus. Like FAM59A, FAM59B may play a role in ligand-mediated signaling pathway of the EGF receptor and the tumorigenesis of cells.

• Western blot analysis of FAM59B in SK-N-SH cell lysate with FAM59B antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
• Immunohistochemistry of FAM59B in human brain tissue with FAM59B antibody at 5 ug/mL.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting