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PI3 Kinase p85/p55 (phospho-Tyr467/199)Antibody #11508

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Catalog No. Package Size Price Quantity
50ul $189.00
100ul $279.00
Availability:Yes
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Description
  • Product NamePI3 Kinase p85/p55 (phospho-Tyr467/199)Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB,IF
  • Species ReactivityHu Ms Rt
  • SpecificityThe antibody detects endogenous level of total PI3 Kinase p85/p55 only when phosphorylated at tyrosine 467/199.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around phosphorylation site of tyrosine 467 (L-Y(p)-E-E-Y) derived from Human PI3 Kinase p85/p55.
  • Target NamePI3 Kinase p85/p55
  • ModificationPhospho
  • Alternative Names    p85, AGM7, p85-ALPHA, p55, p55-GAMMA
  • Accession No. Swiss-Prot:P27986
    Gene ID:5295
  • SDS-PAGE MW 55,85kd
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

Okadaic acid promotes epithelial mesenchymal transition of hepatocellular carcinoma cells by inhibiting protein phosphatase 2A.In J Cell Biochem on 2020 Jan 6. by Kong J, Li D, et al..PMID: 31904141 , , (2020),
PMID: 31587272
Isoliquiritigenin inhibits the proliferation, migration and metastasis of Hep3B cells via suppressing cyclin D1 and PI3K/AKT pathway.In Biosci Rep on 2020 Jan 31; by Huang Y, Liu C, et al..PMID: 31840737, , (2020),
PMID: 31840737
Positive feedback loop of FAM83A/PI3K/AKT/c-Jun induces migration, invasion and metastasis in hepatocellular carcinoma.In Biomed Pharmacother on 2020 Mar; by Liu C, Peng X et al..PMID: 31901550, , (2020),
PMID: 31901550
Combination of Ruthenium Complex and Doxorubicin Synergistically Inhibits Cancer Cell Growth by Down-Regulating PI3K/AKT Signaling Pathway.In Front Oncol on 2020 Feb 18 by Lin K, Rong Y, et al..PMID:32133289, , (2020),
PMID: 32133289
View All Published Papers Dexmedetomidine protects against lipopolysaccharide-induced acute kidney injury by enhancing autophagy through inhibition of the PI3K/AKT/mTOR pathway.In Front Pharmacol. On 2020 Feb 25; by Zhao Y, Feng X, et al..PMID: 32158395, , (2020),
PMID: 32158395
Cardioprotection of ( %2B )-sodium 5-bromo-2-(α-hydroxypentyl) benzoate (BZP) on mouse myocardium I/R injury through inhibiting 12/15-LOX-2 activity. In J Mol Cell Cardiol on 2019 Oct by Xiao Y, Song C, et al..PMID:31362020, , (2019),
PMID: 31362020
An alternatively spliced variant of CXCR3 mediates the metastasis of CD133+ liver cancer cells induced by CXCL9.In Oncotarget on 2016 Mar 22 by Qiang Ding, Yujia Xia et al..PMID:26883105, , (2016),
PMID: 26883105
Angiopoietin-like 3 induces podocyte F-actin rearrangement through integrin α(V)β₃/FAK/PI3K pathway-mediated Rac1 activation.In Biomed Res Int on 2013 by Lin Y, Rao J,et al..PMID:24294595, , (2013),
PMID: 24294595
Angiopoietin-Like 3 Induces Podocyte F-Actin Rearrangement through Integrin /FAK/PI3K Pathway-Mediated Rac1 Activation. In Biomed Res Int on 2013 by Yi Lin, Jia Rao, et al..PMID: 24294595 , , (2013),
PMID: 24294595
Please let us know if you have published research using #11508 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep