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PI3 Kinase p85/p55 (phospho-Tyr467/199)Antibody #11508

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Catalog No. Package Size Price Quantity
50ul $189.00
100ul $279.00
Availability:Yes
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Description
  • Product NamePI3 Kinase p85/p55 (phospho-Tyr467/199)Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB,IF
  • Species ReactivityHu Ms Rt
  • SpecificityThe antibody detects endogenous level of total PI3 Kinase p85/p55 only when phosphorylated at tyrosine 467/199.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around phosphorylation site of tyrosine 467 (L-Y(p)-E-E-Y) derived from Human PI3 Kinase p85/p55.
  • Target NamePI3 Kinase p85/p55
  • ModificationPhospho
  • Alternative Names    p85, AGM7, p85-ALPHA, p55, p55-GAMMA
  • Uniprot P27986
  • Gene ID 5295;
  • Accession No. Swiss-Prot:P27986
    Gene ID:5295
  • SDS-PAGE MW 55,85kd
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

Okadaic acid promotes epithelial mesenchymal transition of hepatocellular carcinoma cells by inhibiting protein phosphatase 2A.In J Cell Biochem on 2020 Jan 6. by Kong J, Li D, et al..PMID: 31904141 , , (2020),
PMID: 31587272
Isoliquiritigenin inhibits the proliferation, migration and metastasis of Hep3B cells via suppressing cyclin D1 and PI3K/AKT pathway.In Biosci Rep on 2020 Jan 31; by Huang Y, Liu C, et al..PMID: 31840737, , (2020),
PMID: 31840737
Positive feedback loop of FAM83A/PI3K/AKT/c-Jun induces migration, invasion and metastasis in hepatocellular carcinoma.In Biomed Pharmacother on 2020 Mar; by Liu C, Peng X et al..PMID: 31901550, , (2020),
PMID: 31901550
Combination of Ruthenium Complex and Doxorubicin Synergistically Inhibits Cancer Cell Growth by Down-Regulating PI3K/AKT Signaling Pathway.In Front Oncol on 2020 Feb 18 by Lin K, Rong Y, et al..PMID:32133289, , (2020),
PMID: 32133289
View All Published Papers Dexmedetomidine protects against lipopolysaccharide-induced acute kidney injury by enhancing autophagy through inhibition of the PI3K/AKT/mTOR pathway.In Front Pharmacol. On 2020 Feb 25; by Zhao Y, Feng X, et al..PMID: 32158395, , (2020),
PMID: 32158395
A Novel Long Non-Coding RNA lnc030 Maintains Breast Cancer Stem Cell Stemness by Stabilizing SQLE mRNA and Increasing Cholesterol Synthesis.In Adv Sci (Weinh) On 2020 Nov 30 by Yilu Qin 1,Yixuan Hou,Shuiqing Liu,et al.., , (2020),
PMID: 33511005 null
Cardioprotection of ( %2B )-sodium 5-bromo-2-(α-hydroxypentyl) benzoate (BZP) on mouse myocardium I/R injury through inhibiting 12/15-LOX-2 activity. In J Mol Cell Cardiol on 2019 Oct by Xiao Y, Song C, et al..PMID:31362020, , (2019),
PMID: 31362020
An alternatively spliced variant of CXCR3 mediates the metastasis of CD133+ liver cancer cells induced by CXCL9.In Oncotarget on 2016 Mar 22 by Qiang Ding, Yujia Xia et al..PMID:26883105, , (2016),
PMID: 26883105
Angiopoietin-like 3 induces podocyte F-actin rearrangement through integrin α(V)β₃/FAK/PI3K pathway-mediated Rac1 activation.In Biomed Res Int on 2013 by Lin Y, Rao J,et al..PMID:24294595, , (2013),
PMID: 24294595
Angiopoietin-Like 3 Induces Podocyte F-Actin Rearrangement through Integrin /FAK/PI3K Pathway-Mediated Rac1 Activation. In Biomed Res Int on 2013 by Yi Lin, Jia Rao, et al..PMID: 24294595 , , (2013),
PMID: 24294595
Please let us know if you have published research using #11508 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep