• Product NameSYNE1 Rabbit Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB,IHC,IF
• Species ReactivityHuman,Mouse,Rat
• Immunogen DescriptionRecombinant protein of human Nesprin 1.
• Alternative Names    8B; AMC3; AMCM; CPG2; ARCA1; EDMD4; KASH1; MYNE1; Nesp1; SCAR8; C6orf98; dJ45H2.2
• Accession No. Uniprot:Q8NF91
  GeneID:23345
• UniprotQ8NF91
• Gene ID23345
• Calculated MW 1011kDa
• SDS-PAGE MW 131KDa
• Formulation PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Storage Store at -20˚C. Avoid freeze / thaw cycles.

• WB 1:500 - 1:2000
  IHC 1:50 - 1:200
  IF 1:50 - 1:200

This gene encodes a spectrin repeat containing protein expressed in skeletal and smooth muscle, and peripheral blood lymphocytes, that localizes to the nuclear membrane. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia 8, also referred to as autosomal recessive cerebellar ataxia type 1 or recessive ataxia of Beauce. Alternatively spliced transcript variants encoding different isoforms have been described.

• Western blot analysis of extracts of Mouse skeletal muscle, using Nesprin 1 antibody.
• Immunohistochemistry of paraffin-embedded rat heart using Nesprin 1 Rabbit pAb.
• Immunofluorescence analysis of NIH/3T3 cells using Nesprin 1 Rabbit pAb.
• Immunohistochemistry of paraffin-embedded mouse kidney using Nesprin 1 Rabbit pAb.
• Immunohistochemistry of paraffin-embedded human colon carcinoma using Nesprin 1 Rabbit pAb.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting