• Product NameCD14 Antibody PE Conjugated
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationPurified by Protein A.
• ApplicationsICC IF
• Species ReactivityHu Ms Rt
• Immunogen DescriptionKLH conjugated synthetic peptide aa 240-270 366 derived from mouse CD14
• ConjugatesPE
• Excitation Emission480,565nm 578nm
• Target NameCD14
• Alternative Names    Monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein; CD14
• Accession No. Swiss-Prot#P10810
  NCBI Gene ID12475
• UniprotP10810
• Gene ID12475;
• Cell Localization Extracellular
• Concentration 1mg ml
• Formulation 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
• Storage Shipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.

• ICC=1:50-200 IF=1:50-200

In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2 TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules (By similarity).

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting