• Product NameCCR7 CD197 Antibody PE Conjugated
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationPurified by Protein A.
• ApplicationsFCM
• Species ReactivityHu Ms Rt
• Immunogen DescriptionKLH conjugated synthetic peptide aa 25-59 379 derived from mouse CCR7
• ConjugatesPE
• Excitation Emission480,565nm 578nm
• Target NameCCR7 CD197
• Alternative Names    EBI1; CCR-7; CD197; Ebi1h; Cdw197; Cmkbr7; CC-CKR-7; C-C chemokine receptor type 7; C-C CKR-7; Epstein-Barr virus-induced G-protein coupled receptor 1; EBV-induced G-protein coupled receptor 1; MIP-3 beta receptor; Ccr7
• Accession No. Swiss-Prot#P47774
  NCBI Gene ID12775
• UniprotP47774
• Gene ID12775;
• Cell Localization Extracellular
• Concentration 1mg ml
• Formulation 10mM Tris Buffered Saline containing 1% BSA, 50% glycerol and 0.09% sodium azide.
• Storage Store at 4C for 12 months.

• FCM: 1:20-100
  

CCR7 is a member of the G protein coupled receptor family (subfamily : chemokine). This receptor was identified as a gene induced by the Epstein Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. CCR7 has been reported to be expressed in blood, bone marrow, lymph node, and intestine. It is particularly expressed in lymphoid tissues and in activated B and T lymphocytes and has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19 ECL) has been reported to be a specific ligand of this receptor. ESTs have been isolated from blood, embryo, lymph node, and thymus libraries.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting