• Product NameCRK Monoclonal Antibody
• Host SpeciesMouse
• ClonalityMonoclonal
• Clone No.3H7-E5-H8
• IsotypeIgG2b
• PurificationAffinity purified
• ApplicationsELISA WB
• Species ReactivityHu D Rb Ms
• Immunogen TypeRecombinant protein
• Immunogen DescriptionPurified recombinant human CRK protein fragments expressed in E.coli.
• Target NameCRK
• Alternative Names    p38, CRKII
• Uniprot P05362
• Gene ID 3383;
• Accession No. Swiss-Prot:P05362
  Gene ID:3383
• Formulation Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol

• Predicted MW: 34kd
  Western blotting: 1:1000
  

The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner.

• Western blot detection of CRK in LNCAP,A431

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting