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ADAMTS5 Antibody

31158
Review: comment rank 5 pdf
  Catalog No. Package Size Price
31158-1 50ul $189.00
31158-2 100ul $279.00

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Description
  • Product Name ADAMTS5 Antibody
  • Host Species Rabbit
  • Clonality Polyclonal
  • Applications ELISA WB IHC
  • Species Reactivity Hu Ms
  • Specificity The antibody detects endogenous level of total ADAMTS5 protein.
  • Immunogen Type Peptide-KLH
  • Immunogen Description Synthetic peptide corresponding to a region derived from 529-541 amino acids of Human A disintegrin and metalloproteinase with thrombospondin motifs 5
  • Target Name ADAMTS5
  • Alternative Names A disintegrin and metalloproteinase with thrombospondin motifs 5, ADMP-2, ADAM-TS5, ADAMTS-5, ADAMTS11, ADAM-TS 5, ADAMTS-11, ADAM-TS 11
  • Accession No. Genbank No.: NP_008969
  • Concentration 1.1 mg/ml
  • Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage Store at -20˚C/1 year
Application Details

Predicted MW: 102kd
ELISA: 1:1000-1:5000
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:10-1:50

Images
  • ADAMTS5 Antibody - SAB | Signalway Antibody

    Gel: 6%SDS-PAGELysate: 40 μgLane 1-2: Hela cell and Human placenta tissue lysatesPrimary antibody: 31158(ADAMTS5 Antibody) at dilution 1/1000Secondary antibody: Goat anti rabbit IgG at 1/5000 dilutionExposure time: 2 minutes

  • ADAMTS5 Antibody - SAB | Signalway Antibody

    The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 31158(ADAMTS5 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: ×200)

Background

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage.

    Please let us know if you have published research using #31158 so that we can cite your reference.
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    Protocol
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    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  
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