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GSK3β(Phospho-Ser9) Antibody #11002

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Catalog No. Package Size Price Quantity
50ul $189.00
100ul $279.00
Availability:Yes
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Description
  • Product NameGSK3β(Phospho-Ser9) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB IHC IF
  • Species ReactivityHu Ms Rt
  • SpecificityThe antibody detects endogenous level of GSK3 beta only when phosphorylated at serine 9.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around phosphorylation site of serine 9 (T-T-S(p)-F-A) derived from Human GSK3β.
  • Target NameGSK3β
  • ModificationPhospho
  • Alternative Names    Factor A, GSK-3 beta, Protein kinase GSK-3-beta, kinase GSK-3 beta
  • Accession No. Swiss-Prot: P49841
    NCBI Protein: NP_001139628.1
  • SDS-PAGE MW 46kd
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Avoid Store at 4°C for short term use.
Application Details
Background

Published Papers

Periostin secreted by cancer-associated fibroblasts promotes cancer stemness in head and neck cancer by activating protein tyrosine kinase 7.In Cell Death Dis.On 2018 Oct 22 by Yu B, Wu K et al..PMID: 30348980, , (2018),
PMID: 30348980
Epithelial Cells Attenuate Toll-Like Receptor-Mediated Inflammatory Responses in Monocyte-Derived Macrophage-Like Cells to Mycobacterium tuberculosis by Modulating the PI3K/Akt/mTOR Signaling Pathway.In Mediators Inflamm.On 2018 Sep by Yang Y, Sun Y et al..PMID:30356420, , (2018),
PMID: 30356420
Gastrokine-2 suppresses epithelial mesenchymal transition through PI3K/AKT/GSK3β signaling in gastric cancer.In Tumour Biol.On 2016 Sep by Dai J, Qian C et al..PMID:27323966, , (2016),
PMID: 27323966
Overexpression of astrocyte-elevated gene-1 is associated with ovarian cancer development and progression.In Mol Med Rep on 2015 Apr by Bo Zhou , Jue Yang et al..PMID:25483832, , (2015),
PMID: 25483832
View All Published Papers Fumosorinone, a Novel PTP1B Inhibitor, Activates Insulin Signaling in Insulin-Resistance HepG2 Cells and Shows Anti-Diabetic Effect in Diabetic KKAy Mice .In Toxicol Appl Pharmacol On 2015 May 15 by Zhi-Qin Liu , Ting Liu et al..PMID: 25796170 , , (2015),
PMID: 25796170
SNAILs promote G1 phase in selected cancer cells.In Int J Oncol on 2015 Nov by Ya-Lan Wu , Jian-Xin Xue et al ..PMID:26352801, , (2015),
PMID: 26352801
A β1/2 Adrenergic Receptor‐Sensitive Intracellular Signaling Pathway Modulates CCL2 Production in Cultured Spinal Astrocytes.In J Cell Physiol on 2014 Mar by Norimitsu Morioka , Hiromi Abe et al..PMID:24037783, , (2014),
PMID: 24037783
Estefan¨ªa de Munck, Emma Mu?noz-S¨¢ez, Bego?na G. Miguel B-N-methylamino-l-alanine causes neurological andpathological phenotypes mimicking Amyotrophic LateralSclerosis (ALS): The first step towards an experimentalmodel for sporadic ALS. , environmental toxicology and pharmacology, 36:243¨C255 (2013),
PMID: 23688553
Yu-fei Pan, Li-wei Dong, Min Wang Signal regulatory protein ¦Á negatively regulates mast-cell activation following Fc¦ÅRI aggregation., Eur. J. Immunol., 43(6):1598¨C1607 (2013),
PMID: 23504624
Phosphoproteome analysis reveals an important role for glycogen synthase kinase-3 in perfluorododecanoic acid-induced rat liver toxicity. In Toxicol Lett on 2013 Mar 27 by Hongxia Zhang, Junjie Hou, et al..PMID: 23353032, , (2013),
PMID: 23353032
β-N-methylamino-l-alanine causes neurological and pathological phenotypes mimicking Amyotrophic Lateral Sclerosis (ALS): The first step towards an experimental model for sporadic ALS. In Environ Toxicol Pharmacol on 2013 Sep by Estefanía de Munck, Emma Muñoz-Sáez, et al..PMID: 23688553, , (2013),
PMID: 23688553
Signal regulatory protein α negatively regulates mast‐cell activation following FcεRI aggregation. In Eur J Immunol on 2013 Jun by Yu-fei Pan, Li-wei Dong, et al..PMID: 23504624, , (2013),
PMID: 23504624
Quantitative proteomics reveals that miR-155 regulates the PI3K-AKT pathway in diffuse large B-cell lymphoma. In Am J Pathol on 2012 Jul by Huang X, Shen Y,et al..PMID:22609116, , (2012),
PMID: 22609116
Yingjuan Yang, Jinzeng Yang, Rongxin Liu Accumulation of ¦Â-catenin by lithium chloride in porcine myoblast cultures accelerates cell differentiation., Molecular Biology Reports, Volume 38, Number 3, Pages 2043-2049 (2011),
PMID: 20857211
Accumulation of β-Catenin by Lithium Chloride in Porcine Myoblast Cultures Accelerates Cell Differentiation.In Mol Biol Rep on 2011 Mar by Yingjuan Yang, Jinzeng Yang,et al..PMID:20857211, , (2011),
PMID: 20857211
Cong REN, Jia-Mou LI, Xin LIN LIPUS Enhance Elongation of Neurites in Rat Cortical Neurons through Inhibition of GSK-3¦Â., Biomedical and Environmental Sciences, 23(3):244-249 (2010),
PMID: 20708505
Wen-Fei Tan, Xue-Zhao Cao, Jun-KeWang Protective effects of lithium treatment for spatial memory deficits induced by tau hyperphosphorylation in splenectomized rats., Clinical and Experimental Pharmacology and Physiology., 37(10):1010¨C1015 (2010),
PMID: 20659131
Protective effects of lithium treatment for spatial memory deficits induced by tau hyperphosphorylation in splenectomized rats.In Clin Exp Pharmacol Physiol on 2010 Oct by Tan WF, Cao XZ,et al..PMID:20659131, , (2010),
PMID: 20659131
LIPUS Enhance Elongation of Neurites in Rat Cortical Neurons Through Inhibition of GSK-3beta.In Biomed Environ Sci on 2010 Jun by Cong Ren, Jia-Mou Li, et al..PMID:20708505, , (2010),
PMID: 20708505
Please let us know if you have published research using #11002 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep