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IRS-1(Ab-636) Antibody #21223

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Datasheet PDF
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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
Availability:Yes
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Description
  • Product NameIRS-1(Ab-636) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • ApplicationsWB IHC IF
  • Species ReactivityHu Ms Rt
  • SpecificityThe antibody detects endogenous level of total IRS-1 protein.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around aa.634~638 (P-M-S-P-K) derived from Human IRS-1.
  • Target NameIRS-1
  • Alternative Names    IRS-1; IRS1;
  • Accession No. Swiss-Prot: P35568
    NCBI Protein: NP_005535.1
  • UniprotP35568
  • Gene ID3667;
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

The role of mitochondrial oxidative stress in the metabolic alterations in diet-induced obesity in rats. In FASEB J on 2019 Nov by Marn-Royo G, Rodrguez C, et al..PMID:31370681, , (2019),
PMID: 31370681
Metabolic inflammation exacerbates dopaminergic neuronal degeneration in response to acute MPTP challenge in type 2 diabetes mice.In Exp Neurol.On 2014 Jan by Wang L, Zhai YQ et al..PMID:24220636, , (2014),
PMID: 24220636
A Preliminary Investigation of the Mechanisms Underlying the Effect of Berberine in Preventing High-Fat Diet-Induced Insulin Resistance in Rats.In J Physiol Pharmacol on 2012 Oct by J-J Gu, F-Y Gao, et al..PMID:23211304, , (2012),
PMID: 23211304
Please let us know if you have published research using #21223 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep