• Product NameCEACAM5 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntibodies were purified by affinity purification using immunogen.
• ApplicationsWB
• Species ReactivityHuman,Mouse
• SpecificityThe antibody detects endogenous level of total CEACAM5 protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionRecombinant protein of human CEACAM5.
• Target NameCEACAM5
• Alternative Names    CEACAM5; CD66e; CEA; DKFZp781M2392; CEACAM5
• Accession No. Swiss-Prot:P06731
  NCBI Gene ID:1048
• UniprotP06731
• Gene ID1048;
• SDS-PAGE MW 77KD
• Concentration 1.0mg/ml
• Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• WB 1:500 - 1:2000

Carcinoembryonic antigen (CEA), also known as CD66e or CEACAM5, is a 180-200 kDa cell surface glycoprotein whose expression is elevated in intestinal carcinomas and other tumors. CEA mediates cell adhesion, though little more is known about its biological activity. Expression of CEA is correlated with tumerogenicity (1), and it has been shown to play a role in cell migration, adhesion and invasion in culture cells, as well as in metastasis in vivo (2).

• Western blot analysis of extracts of various cell lines, using CEACAM5 at 1:1000 dilution.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting