• Product Namep75 NGF Receptor Polyclonal Antibody Cy5.5 Conjugated
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationPurified by Protein A.
• ApplicationsFCM IF(IHC-P) IF(ICC)
• Species ReactivityHu Ms Rt
• Immunogen DescriptionKLH conjugated synthetic peptide aa 287-337 425 derived from rat NGFR
• ConjugatesCy5.5
• Excitation Emission675nm 694nm
• Target Namep75 NGF Receptor
• Alternative Names    p75; LNGFR; p75NTR; RNNGFRR; Tnfrsf16; Tumor necrosis factor receptor superfamily member 16; Gp8-LNGFR; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; p75 ICD; CD271; Ngfr
• Accession No. Swiss-Prot#:P07174
  NCBI Gene ID:24596
• UniprotP07174
• Gene ID24596;
• Cell Localization Cytoplasm
• Concentration 1mg ml
• Formulation Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
• Storage Store at 4C for 12 months.

• FCM:1:20-100
  IF:1:50-200

Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake. Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting