• Product NameFas Ligand Polyclonal Antibody Cy7 Conjugated
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationPurified by Protein A.
• ApplicationsFCM IF(IHC-P)
• Species ReactivityHu Ms Rt
• Immunogen DescriptionKLH conjugated synthetic peptide aa 170-220 281 derived from human Fas Ligand
• ConjugatesCy7
• Excitation Emission743nm 767nm
• Target NameFas Ligand
• Alternative Names    APTL; FASL; CD178; CD95L; ALPS1B; CD95-L; TNFSF6; APT1LG1; Tumor necrosis factor ligand superfamily member 6; Apoptosis antigen ligand; CD95 ligand; Fas antigen ligand; Fas ligand; FASLG
• Accession No. Swiss-Prot#:P48023
  NCBI Gene ID:356
• UniprotP48023
• Gene ID356;
• Cell Localization Extracellular
• Concentration 1mg ml
• Formulation Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
• Storage Store at 4C for 12 months.

• FCM:1:20-100
  IF:1:50-200

Cytokine that binds to TNFRSF6 FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6 FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B DcR3 modulates its effects. The FasL intracellular domain (FasL ICD) cytoplasmic form induces gene transcription inhibition.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting