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NFkB-p65(Phospho-Ser536) Antibody #11014

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Catalog No. Package Size Price Quantity
50ul $189.00
100ul $279.00
Availability:Yes
Total:$789.00
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Description
  • Product NameNFkB-p65(Phospho-Ser536) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB IHC IF
  • Species ReactivityHu Ms Rt
  • SpecificityThe antibody detects endogenous level of NF-kB p65 only when phosphorylated at serine 536.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around phosphorylation site of serine 536 (F-S-S(p)-I-A) derived from Human NFkB-p65.
  • Target NameNFkB-p65
  • ModificationPhospho
  • ModificationPhospho
  • Alternative Names    NFKB3; RELA; TF65; Transcription factor p65; p65
  • Accession No. Swiss-Prot: Q04206
    NCBI Protein: NP_001138610.1
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

CYP4A11 is involved in the development of nonalcoholic fatty liver disease via ROS?induced lipid peroxidation and inflammation.In Int J Mol Med on 2020 Apr by Gao H, Cao Y, et al..PMID:32124935, , (2020),
PMID: 32124935 Induction of apoptosis through extrinsic/intrinsic pathways and suppression of ERK/NF-κB signalling participate in anti-glioblastoma of imipramine.In J Cell Mol Med on 2020 Apr; by Hsu FT, Chiang IT et al..PMID:32149465, , (2020),
PMID: 32149465 Phytoestrogens protect joints in collagen induced arthritis by increasing IgG glycosylation and reducing osteoclast activation.In Int Immunopharmacol on 2020 Mar 12 by Du N, Song L, et al..PMID:32172207, , (2020),
PMID: 32172207 Blockade of extracellular high-mobility group box 1 attenuates inflammation-mediated damage and haze grade in mice with corneal wounds.In Int Immunopharmacol on 2020 Apr 9; by Zhou Y, Wang T, et al..PMID:32279044 , , (2020),
PMID: 32279044 Advanced Glycation End Products Stimulate AngiotensInogen Production in Renal Proximal Tubular Cells. In Am J Med Sci on 2019 Jan by Garagliano JM, Katsurada A, et al..PMID:30466736, , (2019),
PMID: 30466736 Activation of α7-nAChRs protects SH-SY5Y cells from 1-methyl-4-phenylpyridInium-Induced apoptotic cell death via ERK/p53 signalIng pathway. In J Cell Physiol on 2019 Mar 25 by Xu S,Yang B, et al.. PMID:30912145, , (2019),
PMID: 30912145 Nuclear factor I A promotes temozolomide resistance In glioblastoma via activation of nuclear factor κB pathway. In Life Sci on 2019 Nov 1 by Yu X, Wang M, et al..PMID:31614149, , (2019),
PMID: 31614149 Downregulated Expression of Solute Carrier Family 26 Member 6 in NRK-52E Cells Attenuates Oxalate-Induced Intracellular Oxidative Stress.In Oxid Med Cell Longev.On 2018 Oct 10 by Jiang H, Gao X et al..PMID:30405874, , (2018),
PMID: 30405874 Jitakshi De, Robert E. Brown Tissue-microarray based immunohistochemical analysis of survival pathways in nodular sclerosing classical Hodgkin lymphoma as compared with Non-Hodgkin¡¯s lymphoma. , Int J Clin Exp Med, 3(1):55-68 (2010),
PMID: 20369041 Please let us know if you have published research using #11014 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep