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NFkB-p65(Phospho-Ser536) Antibody #11014

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Catalog No. Package Size Price Quantity
50ul $189.00
100ul $279.00
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Description
  • Product NameNFkB-p65(Phospho-Ser536) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB IHC IF
  • Species ReactivityHu Ms Rt
  • SpecificityThe antibody detects endogenous level of NF-kB p65 only when phosphorylated at serine 536.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around phosphorylation site of serine 536 (F-S-S(p)-I-A) derived from Human NFkB-p65.
  • Target NameNFkB-p65
  • ModificationPhospho
  • Alternative Names    NFKB3; RELA; TF65; Transcription factor p65; p65
  • Accession No. Swiss-Prot: Q04206
    NCBI Protein: NP_001138610.1
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

CYP4A11 is involved in the development of nonalcoholic fatty liver disease via ROS?induced lipid peroxidation and inflammation.In Int J Mol Med on 2020 Apr by Gao H, Cao Y, et al..PMID:32124935, , (2020),
PMID: 32124935
Induction of apoptosis through extrinsic/intrinsic pathways and suppression of ERK/NF-κB signalling participate in anti-glioblastoma of imipramine.In J Cell Mol Med on 2020 Apr; by Hsu FT, Chiang IT et al..PMID:32149465, , (2020),
PMID: 32149465
Phytoestrogens protect joints in collagen induced arthritis by increasing IgG glycosylation and reducing osteoclast activation.In Int Immunopharmacol on 2020 Mar 12 by Du N, Song L, et al..PMID:32172207, , (2020),
PMID: 32172207
Blockade of extracellular high-mobility group box 1 attenuates inflammation-mediated damage and haze grade in mice with corneal wounds.In Int Immunopharmacol on 2020 Apr 9; by Zhou Y, Wang T, et al..PMID:32279044 , , (2020),
PMID: 32279044
View All Published Papers Advanced Glycation End Products Stimulate AngiotensInogen Production in Renal Proximal Tubular Cells. In Am J Med Sci on 2019 Jan by Garagliano JM, Katsurada A, et al..PMID:30466736, , (2019),
PMID: 30466736
Activation of α7-nAChRs protects SH-SY5Y cells from 1-methyl-4-phenylpyridInium-Induced apoptotic cell death via ERK/p53 signalIng pathway. In J Cell Physiol on 2019 Mar 25 by Xu S,Yang B, et al.. PMID:30912145, , (2019),
PMID: 30912145
Nuclear factor I A promotes temozolomide resistance In glioblastoma via activation of nuclear factor κB pathway. In Life Sci on 2019 Nov 1 by Yu X, Wang M, et al..PMID:31614149, , (2019),
PMID: 31614149
Downregulated Expression of Solute Carrier Family 26 Member 6 in NRK-52E Cells Attenuates Oxalate-Induced Intracellular Oxidative Stress.In Oxid Med Cell Longev.On 2018 Oct 10 by Jiang H, Gao X et al..PMID:30405874, , (2018),
PMID: 30405874
Pteisolic acid G, a novel ent‑kaurane diterpenoid, inhibits viability and induces apoptosis in human colorectal carcinoma cells.In Oncol Lett on 2017 Nov by Shuangli Qiu ,Xin Wu,et al..PMID: 29113182, , (2017),
PMID: 29113182
Capsular Polysaccharide Is a Main Component of Mycoplasma ovipneumoniae in the Pathogen-Induced Toll-Like Receptor-Mediated Inflammatory Responses in Sheep Airway Epithelial Cells.In Mediators Inflamm on 2017 May 3 by Zhongjia Jiang, Fuyang Song ,et al..PMID: 28553017, , (2017),
PMID: 28553017
Aquaporin-4 mediates communication between astrocyte and microglia: Implications of neuroinflammation in experimental Parkinson’s disease.In Neuroscience. On 2016 Mar 11 by Sun H, Liang R et al..PMID:26774050, , (2016),
PMID: 26774050
Growth inhibition effects of ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid on colorectal carcinoma cells and colon carcinoma-bearing mice.In Mol Med Rep on 2016 Apr by Hua Ye , Qiong Wu et al..PMID:2693577, , (2016),
PMID: 2693577
Knockdown of versican V1 induces a severe inflammatory response in LPS-induced acute lung injury via the TLR2-NF-κB signaling pathway in C57BL/6J mice.In Mol Med Rep on 2016 Jun by Lulu Xu , Tao Xue et al..PMID: 27109786 , , (2016),
PMID: 27109786
Spautin-1 ameliorates acute pancreatitis via inhibiting impaired autophagy and alleviating calcium overload.In Mol Med on 2016 Oct by Juan Xiao , Xueping Feng et al..PMID:27579473, , (2016),
PMID: 27579473
Fluoxetine protects against IL-1β-induced neuronal apoptosis via downregulation of p53.In Neuropharmacology on 2016 Aug et al..PMID:Han Shan, Yaqi Bian et al..PMID:26976669, , (2016),
PMID: 26976669
The Effects of Xiangqing Anodyne Spray on treating acute soft-Tissue injury mainly depend on suppressing activations of AKT and p38 pathways.In Evid Based Complement Alternat Med on 2016 by Shudong Wang , Tao Li et al..PMID:27190541, , (2016),
PMID: 27190541
Protodioscin ameliorates fructose-induced renal injury via inhibition of the mitogen activated protein kinase pathway.In Phytomedicine on 2016 Nov 15 by Jinyang Shen, Xiaolin Yang et al..PMID:27765371, , (2016),
PMID: 27765371
Pre-treatment of Human Umbilical Cord-Derived Mesenchymal Stem Cells With interleukin-6 Abolishes Their Growth-Promoting Effect on Gastric Cancer Cells.In Int J Mol Med on 2015 Feb by Mei Wang , Jie Cai et al..PMID:25483835, , (2015),
PMID: 25483835
Inhibitory effects of eugenol on RANKL-induced osteoclast formation via attenuation of NF-κ B and MAPK pathways.In Connect Tissue Res on 2015 Jun by Vishwa Deepak , Abe Kasonga et al..PMID:25405641, , (2015),
PMID: 25405641
Establishment and characterization of bortezomib-resistant U266 cell line: Constitutive activation of NF-κB-mediated cell signals and/or alterations of ubiquitylation-related genes reduce bortezomib-induced apoptosis.In BMB Rep on 2014 May by Juwon Park, Eun-Kyung Bae et al..PMID: 24286313, , (2014),
PMID: 24286313
Enhanced Survival of Retinal Ganglion Cells Is Mediated by Müller Glial Cell-Derived PEDF .In Exp Eye Res on 2014 Oct by Jan Darius Unterlauft, Thomas Claudepierre et al ..PMID: 25128578, , (2014),
PMID: 25128578
Ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid induces apoptosis and cell cycle arrest in CNE-2Z nasopharyngeal carcinoma cells. In Oncol Rep on 2013 Jun by Kefeng Wu, Yi Liu, et al..PMID: 23563985, , (2013),
PMID: 23563985
Differential apoptosis gene expressions of rhabdomyosarcoma cells in response to enterovirus 71 infection.In BMC Infect Dis on 2012 Nov 28 by Shi W, Li X,et al..PMID:23191987, , (2012),
PMID: 23191987
Dietary Oxidized n-3 PUFA Induce Oxidative Stress and Inflammation: Role of Intestinal Absorption of 4-HHE and Reactivity in Intestinal Cells.In J Lipid Res on 2012 Oct by Manar Awada, Christophe O Soulage,et al..PMID:22865918, , (2012),
PMID: 22865918
NDR1/STK38 potentiates NF‐κB activation by its kinase activity. In Cell Biochem Funct on 2012 Dec by Hu Shi, Dan Lu, et al..PMID: 22674419, , (2012),
PMID: 22674419
Jitakshi De, Robert E. Brown Tissue-microarray based immunohistochemical analysis of survival pathways in nodular sclerosing classical Hodgkin lymphoma as compared with Non-Hodgkin¡¯s lymphoma. , Int J Clin Exp Med, 3(1):55-68 (2010),
PMID: 20369041
Tissue-microarray Based Immunohistochemical Analysis of Survival Pathways in Nodular Sclerosing Classical Hodgkin Lymphoma as Compared With Non-Hodgkin's Lymphoma.In Int J Clin Exp Med on 2010 Jan 30 by Jitakshi De, Robert E Brown,et al..PMID:20369041, , (2010),
PMID: 20369041
Please let us know if you have published research using #11014 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep