• Product NameCtBP1 (Ab-422) Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB IHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total CtBP1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized non-phosphopeptide derived from human CtBP1 around the phosphorylation site of serine 422 (A-P-S(p)-P-G).
• Target NameCtBP1
• Alternative Names    C-terminal binding protein 1; CTBP; EC 1.1.1.-;
• Accession No. Swiss-Prot: Q13363
  NCBI Gene ID: 1487
• UniprotQ13363
• Gene ID1487;
• SDS-PAGE MW 48kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  Immunohistochemistry: 1:50~1:100
  

Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation.

Schaeper U., Proc. Natl. Acad. Sci. U.S.A. 92:10467-10471(1995).
Sewalt R.G.A.B., Mol. Cell. Biol. 19:777-787(1999).
Boyd J.M., EMBO J. 12:469-478(1993).

• Western blot analysis of extracts from Jurkat cells, using CtBP1 (Ab-422) antibody #33281.
• Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using CtBP1 (Ab-422) antibody #33281.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting