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GluR2/3 Antibody

33386
Review: comment rank 5 pdf
  Catalog No. Package Size Price
33386-1 50ul $189.00
33386-2 100ul $279.00

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Description
  • Product Name GluR2/3 Antibody
  • Host Species Rabbit
  • Clonality Polyclonal
  • Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Applications WB IHC
  • Species Reactivity Hu Ms Rt
  • Specificity The antibody detects endogenous levels of total GluR2/3 protein.
  • Immunogen Type Peptide
  • Immunogen Description Synthesized peptide derived from human GluR2/3.
  • Target Name GluR2/3
  • Alternative Names GPRC1C; GRM3; MGR3; Metabotropic glutamate receptor 3 precursor; glutamate receptor metabotropic type 3
  • Accession No. Swiss-Prot: Q14832
    NCBI Gene ID: 2912/2913
  • SDS-PAGE MW 96,99kd
  • Concentration 1.0mg/ml
  • Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20˚C
Application Details

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Images
  • GluR2/3 Antibody - SAB | Signalway Antibody

    Western blot analysis of extracts from mouse brain, using GluR2/3 antibody #33386.

  • GluR2/3 Antibody - SAB | Signalway Antibody

    Immunohistochemical analysis of paraffin-embedded human brain tissue using GluR2/3 antibody #33386.

Background
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.

Akiko Momiyama, J. Physiol., May 2003; 549: 75 - 92.
Mako Narisawa-Saito, PNAS, Mar 1999; 96: 2461.
Karolina Wosik, Brain, Dec 2004; 127: 2636 - 2648.
Chong-Hyun Kim, PNAS, Sep 2001; 98: 11725.
    Please let us know if you have published research using #33386 so that we can cite your reference.
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    Protocol
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    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  
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