• Product NameGluR7 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB IHC
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous levels of total GluR7 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from human GluR7.
• Target NameGluR7
• Alternative Names    EAA5; GLR7; GluR7a; dJ1090M5.1 (glutamate receptor; ionotropic
• Accession No. Swiss-Prot: Q14831
  NCBI Gene ID: 2917
• UniprotQ14831
• Gene ID2917;
• SDS-PAGE MW 100kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  Immunohistochemistry: 1:50~1:100
  

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.

Hans H. Schiffer, J. Neurosci., Dec 2000; 20: 9025.
Nathalie Strutz, J. Neurosci., Jan 2001; 21: 401.
Fr¨¦d¨¦ric Jaskolski, J. Biol. Chem., Jun 2005; 280: 22968 - 22976.
DE Hamassaki-Britto, J. Neurosci., May 1993; 13: 1888.

• Western blot analysis of extracts from HuvEc cells, using GluR7 antibody #33390.
• Immunohistochemical analysis of paraffin-embedded human brain tissue using GluR7 antibody #33390.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting