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STAT3(Ab-705) Antibody #21045

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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
Availability:Yes
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Description
  • Product NameSTAT3(Ab-705) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • ApplicationsWB IHC IF
  • Species ReactivityHu Ms Rt
  • SpecificityThe antibody detects endogenous level of total STAT3 protein.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around aa.703~707(A-P-Y-L-K) derived from Human STAT3.
  • Target NameSTAT3
  • Alternative Names    APRF; Acute-phase response factor; HIES
  • Accession No. Swiss-Prot: P40763
    NCBI Protein: NP_003141.2
  • UniprotP40763
  • Gene ID6774;
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

Magnolol Attenuates Right Ventricular Hypertrophy and Fibrosis in Hypoxia-Induced Pulmonary Arterial Hypertensive Rats Through Inhibition of the JAK2/STAT3 Signaling Pathway. In Front Pharmacol on 2021 Oct 26 by Minyi Fu, Fangmei Luo,et al..PMID:34764873, , (2021),
PMID: 34764873
Effect of STAT3 decoy oligodeoxynucleotides mediated by ultrasound-targeted microbubbles combIned with ultrasound on the growth of squamous cell carcInoma of the esophagus. In Oncol Lett on 2019 Feb by Zhang Y, Zhang M, et al..PMID:30675281, , (2019),
PMID: 30675281
A thiazole-derived oridonIn analogue exhibits antitumor activity by directly and allosterically InhibitIng STAT3. In J Biol Chem on 2019 Nov 15;by Shen X, Zhao L,et al..PMID:31594861, , (2019),
PMID: 31594861
A novel IFIH1 mutation in the pincer domain underlies the clinical features of both Aicardi-Goutires and Singleton-Merten syndromes in a single patient.In Br J Dermatol. On 2018 Feb by Takeichi T, Katayama C et al..PMID:29270977, , (2018),
PMID: 29270977
View All Published Papers Regulatory Effect of Baicalin on the Imbalance of Th17/Treg Responses in Mice With Allergic Asthma. In J Ethnopharmacol on 2017 Aug 17 by Lu Xu , Jinxia Li, et al..PMID: 28709893 , , (2017),
PMID: 28709893
Girdin/GIV is upregulated by cyclic tension, propagates mechanical signal transduction, and is required for the cellular proliferation and migration of MG-63 cells.In Biochem Biophys Res Commun.On 2015 Aug 21 by Hu JT, Li Y et al..PMID:26163263, , (2015),
PMID: 26163263
Pyruvate kinase M2 accelerates pro-inflammatory cytokine secretion and cell proliferation induced by lipopolysaccharide in colorectal cancer. In Cell Signal on 2015 Jul by Peng Yang, Zongwei Li, et al..PMID:25778902, , (2015),
PMID: 25778902
Pyruvate kinase M2 facilitates colon cancer cell migration via the modulation of STAT3 signalling.In Cell Signal on 2014 Sep by Peng Yang, Zongwei Li et al..PMID:24686087, , (2014),
PMID: 24686087
Atrial natriuretic peptide suppresses Th17 development through regulation of cGMP-dependent protein kinase and PI3K�CAkt signaling pathways. In Regul Pept on 2013 Feb 10 by Libing Ma, Jinxiu Li, et al..PMID: 23327998, , (2013),
PMID: 23327998
Hydrogen sulfide postconditioning protects isolated rat hearts against ischemia and reperfusion injury mediated by the JAK2/STAT3 survival pathway.In Braz J Med Biol Res on 2012 Oct by Luan HF, Zhao ZB,et al..PMID:22948409, , (2012),
PMID: 22948409
A Guanidine-Rich Regulatory Oligodeoxynucleotide Improves type-2 Diabetes in Obese Mice by Blocking T-cell Differentiation. In EMBO Mol Med on 2012 Oct by Xiang Cheng, Jing Wang, et al..PMID:23027613 , , (2012),
PMID: 23027613
Canonical notch pathway protects hepatocytes from ischemia/reperfusion injury in mice by repressing reactive oxygen species production through JAK2/STAT3 signaling.In Hepatology on 2011 Sep 2 by Yu HC, Qin HY,et al..PMID:21633967, , (2011),
PMID: 21633967
Overexpression of LEDGF/DFS70 Induces IL-6 via p38 Activation in HaCaT Cells, Similar to That Seen in the Psoriatic Condition.In J Invest Dermatol on 2010 Dec by Takuya Takeichi, Kazumitsu Sugiura, et al..PMID:20631726, , (2010),
PMID: 20631726
Please let us know if you have published research using #21045 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep