• Product NameSynuclein γ Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB IHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total synuclein γ protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from human synuclein γ.
• Target NameSynuclein γ
• Alternative Names    BCSG1; PERSYN; BREAST CANCER-SPECIFIC GENE 1;
• Accession No. Swiss-Prot: O76070
  NCBI Gene ID: 6623
• UniprotO76070
• Gene ID6623;
• SDS-PAGE MW 20kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  Immunohistochemistry: 1:50~1:100
  

Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases By similarity. May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway By similarity.

Heather Snyder, J. Biol. Chem., Mar 2005; 280: 7562 - 7569.
Anja Leona Biere, J. Biol. Chem., Oct 2000; 275: 34574.
Natalia Ninkina, Mol. Cell. Biol., Nov 2003; 23: 8233 - 8245.
Zhong-Zong Pan, J. Biol. Chem., Sep 2002; 277: 35050 - 35060.

• Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Synuclein γ antibody #33493.
• Western blot analysis of extracts from HT29 cells, using Synuclein γ antibody #33493.
• Western blot analysis of extracts from cos-7 cells (Lane 2), using Synuclein γ antiobdy #33493. The lane on the left is treated with synthesized peptide.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting