• Product NameKLF11 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total KLF11 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from Internal of human KLF11.
• Target NameKLF11
• Alternative Names    KLF11; Krueppel-like factor 11; TGFB-inducible early growth response protein 2; TIEG-2; transforming growth factor-beta-inducible early growth response protein 2
• Accession No. Swiss-Prot: O14901
  NCBI Gene ID: 8462
• UniprotO14901
• Gene ID8462;
• SDS-PAGE MW 55kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Transcription factor. Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth. Represses transcription of SMAD7 which enhances TGF-beta signaling. Induces apoptosis.

Cook T., J. Biol. Chem. 273:25929-25936(1998).
Asano H., Mol. Cell. Biol. 19:3571-3579(1999).
Neve B., Proc. Natl. Acad. Sci. U.S.A. 102:4807-4812(2005).

• Western blot analysis of extracts from 293 cells, Jurkat cells and HuvEc cells, using KLF11 antibody #33571.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting