• Product NameDNA Polymerase ζ Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsIHC
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total DNA Polymerase ζ protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human DNA Polymerase ζ.
• Target NameDNA Polymerase ζ
• Alternative Names    DNA polymerase zeta catalytic subunit; DPOLZ; DPOZ; EC 2.7.7.7; POLZ
• Accession No. Swiss-Prot: O60673
  NCBI Gene ID: 5980
• UniprotO60673
• Gene ID5980;
• SDS-PAGE MW 352kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1:50~1:100
  

Interacts with MAD2L2 to form the error prone DNA polymerase zeta involved in translesion DNA synthesis.

Gibbs P.E.M., Proc. Natl. Acad. Sci. U.S.A. 95:6876-6880(1998).
Lin W., Mutat. Res. 433:89-98(1999).
Morelli C., Cytogenet. Cell Genet. 83:18-20(1998).

• Immunohistochemistry analysis of paraffin-embedded human brain tissue, using DNA Polymerase ζ antibody #33602.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting