• Product NameHEXB Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB IHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total HEXB protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from C-terminal of human HEXB.
• Target NameHEXB
• Alternative Names    Beta-hexosaminidase beta chain [Precursor]; EC 3.2.1.52; N-acetyl-beta-glucosaminidase; Beta-N-acetylhexosaminidase; Hexosaminidase B
• Accession No. Swiss-Prot: P07686
  NCBI Gene ID: 3074
• UniprotP07686
• Gene ID3074;
• SDS-PAGE MW 63kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  Immunohistochemistry: 1:50~1:100
  

Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues.

Korneluk R.G., J. Biol. Chem. 261:8407-8413(1986).
Neote K., Genomics 3:279-286(1988).
Proia R.L., Proc. Natl. Acad. Sci. U.S.A. 85:1883-1887(1988).

• Western blot analysis of extracts from Jurkat cells, using HEXB antibody #33657.
• Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using HEXB antibody #33657.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting