• Product NameEGR2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous levels of total EGR2 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from C-terminal of human EGR2.
• Target NameEGR2
• Alternative Names    AT591; CMT1D; CMT4E; DKFZp686J1957; early growth response 2
• Accession No. Swiss-Prot: P11161
  NCBI Gene ID: 1959
• UniprotP11161
• Gene ID1959;
• SDS-PAGE MW 50kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. E3 SUMO-protein ligase helping SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity.

Joseph L.J., Proc. Natl. Acad. Sci. U.S.A. 85:7164-7168(1988).
Warner L.E., Nat. Genet. 18:382-384(1998).
Bechtel S., BMC Genomics 8:399-399(2007).

• Western blot analysis of extracts from K562 cells, using EGR2 antibody #33670.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting