• Product NameERCC5 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total ERCC5 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human ERCC5.
• Target NameERCC5
• Alternative Names    DNA excision repair protein ERCC-5; DNA-repair protein complementing XP-G cells; ERCC5; XPGC; Xeroderma pigmentosum group G complementing protein
• Accession No. Swiss-Prot: P28715
  NCBI Gene ID: 2073
• UniprotP28715
• Gene ID2073;
• SDS-PAGE MW 130kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000

Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3'incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too.

Scherly D., Nature 363:182-185(1993).
Shiomi T., Mutat. Res. 314:167-175(1994).
Macinnes M.A., Mol. Cell. Biol. 13:6393-6402(1993).

• Western blot analysis of extracts from colo cells, using ERCC5 antibody #33738.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting