• Product NameGlucokinase Regulator Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous levels of total Glucokinase Regulator protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human Glucokinase Regulator.
• Target NameGlucokinase Regulator
• Alternative Names    Glucokinase regulatory protein; Glucokinase regulator;
• Accession No. Swiss-Prot: Q14397
  NCBI Gene ID: 2646
• UniprotQ14397
• Gene ID2646;
• SDS-PAGE MW 68kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.

Warner J.P., Mamm. Genome 6:532-536(1995).
Hayward B.E., Genomics 49:137-142(1998).
Rieder M.J., Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.

• Western blot analysis of extracts from mouse heart cells and rat heart cells, using Glucokinase Regulator antibody #33879.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting