• Product NameELAC2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total ELAC2 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human ELAC2.
• Target NameELAC2
• Alternative Names    Zinc phosphodiesterase ELAC protein 2; EC 3.1.26.11; Ribonuclease Z 2; RNase Z 2; tRNase Z 2
• Accession No. Swiss-Prot: Q9BQ52
  NCBI Gene ID: 60528
• UniprotQ9BQ52
• Gene ID60528;
• SDS-PAGE MW 92kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1:50~1:100
  

Zinc phosphodiesterase, which displays mitochondrial tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

Tavtigian S.V., Nat. Genet. 27:172-180(2001).
Ota T., Nat. Genet. 36:40-45(2004).
Takaku H., Nucleic Acids Res. 31:2272-2278(2003).

• Immunohistochemistry analysis of paraffin-embedded human brain tissue, using ELAC2 antibody #34041.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting