• Product NameIKZF3 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total IKZF3 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human IKZF3.
• Target NameIKZF3
• Alternative Names    AIOL; IKZF3; ZNFN1A3; zinc finger protein Aiolos;
• Accession No. Swiss-Prot: Q9UKT9
  NCBI Gene ID: 22806
• UniprotQ9UKT9
• Gene ID22806;
• SDS-PAGE MW 62kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner.

Hosokawa Y., Genomics 61:326-329(1999).
Liippo J.P., Eur. J. Immunol. 31:3469-3474(2001).
Perdomo J., J. Biol. Chem. 275:38347-38354(2000).

• Western blot analysis of extracts from COLO cells, using IKZF3 antibody #34112.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting