• Product NameMAFF Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsIHC
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total MAFF protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human MAFF.
• Target NameMAFF
• Alternative Names    Transcription factor MafF; V-maf musculoaponeurotic fibrosarcoma oncogene homolog F; U-Maf; MAFF;
• Accession No. Swiss-Prot: Q9ULX9
  NCBI Gene ID: 23764
• UniprotQ9ULX9
• Gene ID23764;
• SDS-PAGE MW 18kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1:50~1:100
  

Interacts with the upstream promoter region of the oxytocin receptor gene. May be a transcriptional enhancer in the up-regulation of the oxytocin receptor gene at parturition. Since it lacks a putative transactivation domain, it may behave as a transcriptional repressor when it dimerize among himself. May also serve as a transcriptional activator by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. May be involved in the cellular stress response.

Ota T., Nat. Genet. 36:40-45(2004).
Moran J.A., Biochem. J. 361:371-377(2002).
Dunham I., Nature 402:489-495(1999).

• Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using MAFF antibody #34118.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting