• Product NameJIP3 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB IF
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total JIP3 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human JIP3.
• Target NameJIP3
• Alternative Names    C-jun-amino-terminal kinase interacting protein 3; JIP-3; JIP3; JNK MAP kinase scaffold protein 3; JNK-interacting protein 3
• Accession No. Swiss-Prot: Q9UPT6
  NCBI Gene ID: 23162
• UniprotQ9UPT6
• Gene ID23162;
• SDS-PAGE MW 147kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  Immunofluorescence: 1:100~1:500

The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins By similarity. UniProtKB Q9ESN9

Hattori A., DNA Res. 7:357-366(2000).
Martin J., Nature 432:988-994(2004).
Beausoleil S.A., Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).

• Western blot analysis of extracts from HeLa cells, using JIP3 antibody #34121.
• Immunofluorescence analysis of HeLa cells, using JIP3 antibody #34121.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting