• Product NameDYR1B Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total DYR1B protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human DYR1B.
• Target NameDYR1B
• Alternative Names    DYR1B; Dual-specificity tyrosine-phosphorylation regulated kinase 1B; EC 2.7.12.1; MIRK; Mirk protein kinase
• Accession No. Swiss-Prot: Q9Y463
  NCBI Gene ID: 9149
• UniprotQ9Y463
• Gene ID9149;
• SDS-PAGE MW 70kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Dual-specificity kinase which possesses both serine/ threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments.

Lee K., Cancer Res. 60:3631-3637(2000).
Grimwood J., Nature 428:529-535(2004).
Lim S., . Biol. Chem. 277:25040-25046(2002).

• Western blot analysis of extracts from Jurkat cells, using DYR1B antibody #34135.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting