• Product NameADCY1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total ADCY1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human ADCY1.
• Target NameADCY1
• Alternative Names    ATP pyrophosphate-lyase; CYA1; Ca/calmodulin activated adenylyl cyclase; EC 4.6.1.1; adenylate cyclase 1
• Accession No. Swiss-Prot: Q08828
  NCBI Gene ID: 107
• UniprotQ08828
• Gene ID107;
• SDS-PAGE MW 130kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina By similarity.

Hillier L.W., Nature 424:157-164(2003).
Villacres E.C., Genomics 16:473-478(1993).

• Western blot analysis of extracts from COLO205 cells, using ADCY1 antibody #34159.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting