• Product NameCytochrome P450 2D6 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total Cytochrome P450 2D6 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human Cytochrome P450 2D6.
• Target NameCytochrome P450 2D6
• Alternative Names    Cytochrome P450 2D6; EC 1.14.14.1; CYPIID6; P450-DB1; Debrisoquine 4-hydroxylase
• Accession No. Swiss-Prot: P10635
  NCBI Gene ID: 1565
• UniprotP10635
• Gene ID1565;
• SDS-PAGE MW 55kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants.

Tyndale R., Pharmacogenetics 1:26-32(1991).
Yokota H., Pharmacogenetics 3:256-263(1993).
Evert B., Naunyn Schmiedebergs Arch. Pharmacol. 350:434-439(1994).

• Western blot analysis of extracts from HT-29 cells, using Cytochrome P450 2D6 antibody #34237.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting