• Product NameFGF23 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB IF
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total FGF23 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human FGF23.
• Target NameFGF23
• Alternative Names    Fibroblast growth factor 23; FGF-23; Tumor-derived hypophosphatemia-inducing factor; HYPF;
• Accession No. Swiss-Prot: Q9GZV9
  NCBI Gene ID: 8074
• UniprotQ9GZV9
• Gene ID8074;
• SDS-PAGE MW 27kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  Immunofluorescence: 1:100~1:500

Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL By similarity. Acts directly on the parathyroid to decrease PTH secretion By similarity. Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.

Yamashita T., Biochem. Biophys. Res. Commun. 277:494-498(2000).
White K.E., Nat. Genet. 26:345-348(2000).
Shimada T., Proc. Natl. Acad. Sci. U.S.A. 98:6500-6505(2001).

• Western blot analysis of extracts from JK cells, using FGF23 antiobdy #34248.
• Immunofluorescence analysis of HuvEc cells, using FGF23 antibody #34248.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting