• Product NameSerpin B5 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous levels of total Serpin B5 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human Serpin B5.
• Target NameSerpin B5
• Alternative Names    Serpin B5 [Precursor]; Maspin; Protease inhibitor 5; SERPINB5; PI5
• Accession No. Swiss-Prot: P36952
  NCBI Gene ID: 5268
• UniprotP36952
• Gene ID5268;
• SDS-PAGE MW 40kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

Zou Z., Science 263:526-529(1994).
Pemberton P.A., J. Biol. Chem. 270:15832-15837(1995).
Law R.H., J. Biol. Chem. 280:22356-22364(2005).

• Western blot analysis of extracts from HeLa cells, using Serpin B5 antibody #34298.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting