• Product NamePSMC6 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total PSMC6 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human PSMC6.
• Target NamePSMC6
• Alternative Names    26S protease regulatory subunit S10B; proteasome 26S subunit ATPase 6; proteasome subunit p42; PRS10; SUG2
• Accession No. Swiss-Prot: P62333
  NCBI Gene ID: 5706
• UniprotP62333
• Gene ID5706;
• SDS-PAGE MW 44kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.

Fujiwara T., FEBS Lett. 387:184-188(1996).
Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Demartino G.N., J. Biol. Chem. 271:3112-3118(1996).

• Western blot analysis of extracts from RAW264.7 cells, 293 cells and HepG2 cells, using PSMC6 antibody #34306.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting