Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA.
Wiemann S., Genome Res. 11:422-435(2001).
Zhang Q.-H., Genome Res. 10:1546-1560(2000).The MGC Project Team; Genome Res. 14:2121-2127(2004).