• Product NameCHRNB1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total CHRNB1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from N-terminal of human CHRNB1.
• Target NameCHRNB1
• Alternative Names    Acetylcholine receptor subunit beta;
• Accession No. Swiss-Prot: P11230
  NCBI Gene ID: 1140
• UniprotP11230
• Gene ID1140;
• SDS-PAGE MW 55kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

Beeson D.M.W., Nucleic Acids Res. 17:4391-4391(1989).
Gomez C.M., Ann. Neurol. 39:712-723(1996).
Engel A.G., Hum. Mol. Genet. 5:1217-1227(1996).

• Western blot analysis of extracts from HeLa cells, using CHRNB1 antibody #34374.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting