• Product NameADH7 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total ADH7 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human ADH7.
• Target NameADH7
• Alternative Names    ADH-4; alcohol dehydrogenase class 4 mu/sigma; alcohol dehydrogenase class IV mu/sigma; EC 1.1.1.1; gastric alcohol dehydrogenase
• Accession No. Swiss-Prot: P40394
  NCBI Gene ID: 131
• UniprotP40394
• Gene ID131;
• SDS-PAGE MW 40kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Could function in retinol oxidation for the synthesis of retinoic acid, a hormone important for cellular differentiation. Medium-chain (octanol) and aromatic (m-nitrobenzaldehyde) compounds are the best substrates. Ethanol is not a good substrate but at the high ethanol concentrations reached in the digestive tract, it plays a role in the ethanol oxidation and contributes to the first pass ethanol metabolism.

Satre M.A., J. Biol. Chem. 269:15606-15612(1994).
Zgombic-Knight M., J. Biol. Chem. 270:4305-4311(1995).
Farres J., Eur. J. Biochem. 224:549-557(1994).

• Western blot analysis of extracts from COS cells, using ADH7 antibody #34396.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting