• Product NameAPLP2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total APLP2 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human APLP2.
• Target NameAPLP2
• Alternative Names    Amyloid protein homolog; Amyloid-like protein 2 precursor; APLP2; APP2; APPH
• Accession No. Swiss-Prot: Q06481
  NCBI Gene ID: 334
• UniprotQ06481
• Gene ID334;
• SDS-PAGE MW 87kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts By similarity.

Sprecher C.A., Biochemistry 32:4481-4486(1993).
Wasco W., Nat. Genet. 5:95-99(1993).
von der Kammer H., DNA Cell Biol. 13:1137-1143(1994).

• Western blot analysis of extracts from A549 cells and RAW264.7 cells, using APLP2 antibody #34415.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting